Table 2.
Correlation of infiltration of TIL and expression of PD-L1 in tumor tissues of 83 NPC patients
| PD-L1 in Tumor cells | *P | ||
|---|---|---|---|
| – | + | ||
| Total TIL | |||
| High | 11 (24)♣ | 35 (76) | 0.230 |
| Low | 14 (38) | 23 (62) | |
| CD3+ TIL | |||
| High | 9 (19) | 39 (81) | 0.015 |
| Low | 16 (46) | 19 (54) | |
| CD8+ TIL | |||
| High | 13 (23) | 43 (77) | 0.073 |
| Low | 12 (44) | 15 (56) | |
| FOXP3+/CD3+ TIL | |||
| Low (≤ 10% of CD3 + TIL) | 15 (28) | 38 (72) | |
| High (> 10% of CD3 + TIL) | 10 (33) | 20 (67) | 0.629 |
| ⋄PD-1 +/CD3+ TIL | |||
| Low (< 10% of CD3 + TIL) | 9 (27) | 24 (73) | |
| High (≥ 10% of CD3 + TIL) | 16 (35) | 30 (65) | 0.625 |
(+ and -) are number of positive and negative patients, *P values in bold represent significant data as calculated using Fisher’s Exact Test, ♣Numbers between brackets are the percentages of patients, ⋄ Four samples had unknown PD-1 status