Table 2.

Combination interaction of phenolic compounds with commercial antibiotics against Salmonella enterica serovar Typhimurium (ATCC14028)

Drug Combinations	FIC Index (X)
Galic acid + Ampicillin	0.625 (A)
Galic acid + Amoxicillin	1.004 (I)
Galic acid + Ceftiofur	0.563 (A)
Galic acid + Penicillin G	1.016 (I)
Galic acid + Cefotaxime	1.004 (I)
Galic acid + Erythromycin	1.001 (I)
Galic acid + Thiamphenicol	0.625 (A)
Galic acid + Marbofloxacin	1.002 (I)
Hamamelitannin + Ampicillin	1.002 (I)
Hamamelitannin + Amoxicillin	1.001 (I)
Hamamelitannin + Ceftiofur	0.625 (A)
Hamamelitannin + Penicillin G	1.004 (I)
Hamamelitannin + Cefotaxime	0.563 (A)
Hamamelitannin + Erythromycin	1.001 (I)
Hamamelitannin + Thiamphenicol	1.002 (I)
Hamamelitannin + Marbofloxacin	0.563 (A)
Epicatechin + Ampicillin	0.750 (A)
Epicatechin + Amoxicillin	1.001 (I)
Epicatechin + Ceftiofur	0.625 (A)
Epicatechin + Penicillin G	1.004 (I)
Epicatechin + Cefotaxime	0.750 (A)
Epicatechin + Erythromycin	1.016 (I)
Epicatechin + Thiamphenicol	1.016 (I)
Epicatechin + Marbofloxacin	1.004 (I)
Epicatechin gallate + Ampicillin	0.563 (A)
Epicatechin gallate + Amoxicillin	1.002 (I)
Epicatechin gallate + Ceftiofur	1.001 (I)
Epicatechin gallate + Penicillin G	0.502 (A)
Epicatechin gallate + Cefotaxime	1.004 (I)
Epicatechin gallate + Erythromycin	0.500 (S)
Epicatechin gallate + Thiamphenicol	0.504 (A)
Epicatechin gallate + Marbofloxacin	1.008 (I)
Epigallocatechin + Ampicillin	1.001 (I)
Epigallocatechin + Amoxicillin	1.004 (I)
Epigallocatechin + Ceftiofur	0.625 (A)
Epigallocatechin + Penicillin G	1.008 (I)
Epigallocatechin + Cefotaxime	0.502 (A)
Epigallocatechin + Erythromycin	0.516 (A)
Epigallocatechin + Thiamphenicol	1.004 (I)
Epigallocatechin + Marbofloxacin	0.502 (A)

FIC, fractional inhibitory concentration; Synergy, X ≤ 0.5; Additive, 0.5 < X ≤ 1; Indifferent, 1 < X ≤ 2; Antagonist, X > 2; (A), (I) and (S) stand for Additive, Indifferent and Synergy, respectively