Table 4.
Predictive factors for uPCR < 1 mg/mg at 5 years posttreatment
Model 1a | Model 2b | Model 3c | |||||||
---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | |
ln(uAGT/Cr) (μg/g) | 0.971 | 0.654–1.441 | 0.882 | 1.548 | 0.868–2.760 | 0.139 | 0.898 | 0.586–1.374 | 0.620 |
Δln(uAGT/Cr) (μg/g) d | 0.361 | 0.195–0.668 | 0.001 | 0.287 | 0.126–0.654 | 0.003 | 0.379 | 0.201–0.715 | 0.003 |
ln(uR/Cr) (pg/g) | 0.945 | 0.652–1.363 | 0.753 | 1.105 | 0.733–1.666 | 0.633 | 1.020 | 0.691–1.505 | 0.922 |
Abbreviations: CI confidence interval, OR odds ratio, uAGT/Cr urinary angiotensinogen/creatinine ratio, uR/Cr urinary renin/creatinine ratio
aModel 1: Adjusted for diabetes mellitus, hypertension, and baseline eGFR
bModel 2: Adjusted for baseline uPCR, diabetes mellitus, hypertension, and baseline eGFR
cModel 3: Adjusted for ΔuPCR at 24 weeks (uPCR at 24 weeks - baseline uPCR), diabetes mellitus, hypertension, and baseline eGFR
dΔln(uAGT/Cr) = [ln(uAGT/Cr) at 24 weeks] - [baseline ln(uAGT/Cr)]