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. 2020 May 1;21:180. doi: 10.1186/s12882-020-01825-6

Table 4.

Predictive factors for uPCR < 1 mg/mg at 5 years posttreatment

Model 1a Model 2b Model 3c
OR 95% CI P OR 95% CI P OR 95% CI P
ln(uAGT/Cr) (μg/g) 0.971 0.654–1.441 0.882 1.548 0.868–2.760 0.139 0.898 0.586–1.374 0.620
Δln(uAGT/Cr) (μg/g) d 0.361 0.195–0.668 0.001 0.287 0.126–0.654 0.003 0.379 0.201–0.715 0.003
ln(uR/Cr) (pg/g) 0.945 0.652–1.363 0.753 1.105 0.733–1.666 0.633 1.020 0.691–1.505 0.922

Abbreviations: CI confidence interval, OR odds ratio, uAGT/Cr urinary angiotensinogen/creatinine ratio, uR/Cr urinary renin/creatinine ratio

aModel 1: Adjusted for diabetes mellitus, hypertension, and baseline eGFR

bModel 2: Adjusted for baseline uPCR, diabetes mellitus, hypertension, and baseline eGFR

cModel 3: Adjusted for ΔuPCR at 24 weeks (uPCR at 24 weeks - baseline uPCR), diabetes mellitus, hypertension, and baseline eGFR

dΔln(uAGT/Cr) = [ln(uAGT/Cr) at 24 weeks] - [baseline ln(uAGT/Cr)]