Figure 1. The exposome concept.

The exposome is an integrated function of exposure on our body including what we eat and do, our experiences, and where we live and work. The chemical exposome is an important and integral part of the exposome concept. Examples of external stressors are adapted from (39). These stressors are reflected in internal biological perturbations (Figure 3); thus, exposures are not restricted to chemicals (toxicants) entering the body, but also include chemicals produced by biological and other natural processes.