TABLE 3.

Mutations in embCAB among 118 M. tuberculosis isolates.

Mutations		No. of isolates
embA UR	embB	MICs (μ g/ml)
		≤0.5	1.0	2.0	4.0	8.0	16.0	≥32.0
G(-43)C		0	0	0	0	1	0	0
C(-11)T		0	0	0	0	1	0	0
C(-16)G	Met306Ile	0	0	0	0	0	1	0
C(-16)T	Met306Ile	0	0	0	0	1	0	1
C(-16)A	Met306Ile	0	0	0	0	1	0	0
	Met306Ile/Gly406Asp	0	0	0	0	0	1	0
	Met306Ile/Gly406Ser	0	0	0	0	1	0	0
	Met306Ile	1	0	0	4	2	2	0
G(-5)A	Met306Leu	0	0	0	0	1	0	0
	Met306Leu	0	1	0	0	1	2	0
G(-43)C	Met306Val	0	0	0	0	0	0	1
C(-16)G	Met306Val	0	0	0	0	0	1	0
C(-12)T	Met306Val	0	0	0	0	1	0	1
C(-11)A	Met306Val	0	0	0	0	0	0	2
	Met306Val/Gln497His	0	0	0	0	0	0	1
	Met306Val	0	0	1	6	18	3	3
	Tyr319Cys	0	0	0	0	2	1	0
	Asp328Tyr	0	0	0	1	0	1	0
C(-12)T	Gly406Ala	0	0	0	0	0	0	1
	Gly406Ala	0	0	0	0	1	1	0
	Gly406Asp	0	0	2	0	0	0	0
	Ser412Pro	0	0	0	0	0	0	1
	Gln497Arg	0	0	0	0	0	1	0
NM	NM	20	8	5	8	3	1	1

Abbreviation: NM, no mutation.