Table II:
Deuterium exchange kinetics for protein formulations fitted to the mono-exponential model in Equation 1. (mean ± SD, n=3)
Formulation | Dmax | k (h−1) |
---|---|---|
Myo Only | 34.2 ± 1.6 | 0.067 ± 0.015 |
Myo Suc | 8.8 ± 0.4 | 0.043 ± 0.008 |
Myo Tre | 9.6 ± 0.5 | 0.058 ± 0.013 |
Myo Dex 20K | 19.6 ± 1.0 | 0.049 ± 0.012 |
Myo Dex 70K | 20.6 ± 0.9 | 0.045 ± 0.009 |
BSA Only | 197 ± 6.5 | 0.028 ± 0.005 |
BSA Suc | 78.7 ± 5.1 | 0.011 ± 0.002 |
BSA Tre | 85.7 ± 4.3 | 0.016 ± 0.002 |
BSA Dex 20K | 139.3 ± 2.4 | 0.019 ± 0.003 |
BSA Dex 70K | 155.8 ± 5.1 | 0.019 ± 0.003 |