Table 3.
Comparison Between Patients With and Without Complete Fibrinolysis Shutdown
| Variable | No fibrinolysis shutdown | Fibrinolysis shutdown | p Value |
|---|---|---|---|
| Age, y, median (IQR) | 56 (46–58) | 53 (45–62) | 0.859 |
| BMI, kg/m2, median (IQR) | 30 (27–38) | 30 (28–33) | 0.760 |
| Cardiac arrhythmias, % | 10 | 4 | 0.570 |
| Hypertension, % | 53 | 44 | 0.761 |
| Diabetes mellitus, % | 37 | 44 | 0.760 |
| Hyperlipidemia, % | 42 | 12 | 0.035∗ |
| COPD, % | 5 | 4 | 0.999 |
| Asthma, % | 0 | 16 | 0.122 |
| Smoking/vaping, % | 0 | 8 | 0.498 |
| Alcohol or substance use disorder, % | 0 | 0 | 0.999 |
| Immunosuppression, % | 0 | 4 | 0.999 |
| None of the above, % | 43 | 57 | 0.999 |
| Platelet count, 109/L, median (IQR) | 243 (198–341) | 226 (184–280) | 0.343 |
| Prothrombin time, s, median (IQR) | 14 (13–15) | 16 (14–16) | 0.117 |
| Activated partial thromboplastin time, s, median (IQR) | 31 (30–40) | 37 (34–49) | 0.146 |
| Fibrinogen, mg/dL, median (IQR) | 728 (563–944) | 649 (556–773) | 0.360 |
| d-dimer, ng/mL fibrinogen equivalent, median (IQR) | 2,685 (1,850–8,740) | 2,720 (1,595–17,270) | 0.355 |
| C-reactive protein, mg, median (IQR) | 181 (73–271) | 127 (87–250) | 0.485 |
| R-time, min, median (IQR) | 7.1 (4.5–7.8) | 6 (4.5–10.2) | 0.537 |
| Angle, degrees, median (IQR) | 74 (72–75) | 67(63–72) | 0.019∗ |
| Maximum amplitude, mm, median (IQR) | 77 (72–78) | 73 (66–78) | 0.999 |
IQR, interquartile range.
∗
Statistically significant.