Table 2.

The comparison of nucleotide and amino acid similarity of pangolin-hCoV and bat-hCoV with hCoV.

Gene(s)	Nucleotide		Amino acid
	Pangolin hCoV/hCoV	Bat hCoV/hCoV	Pangolin hCoV/hCoV	Bat hCoV/hCoV
Nsp1	91.68	96.29	95	96.11
Nsp2	88.47	95.4	93.89	98.28
Nsp3	88.7	95.61	92.4	96.66
Nsp4	90.13	95.87	97.6	99.6
Nsp5	93.98	95.86	99.35	99.67
Nsp6	92.87	95.98	98.97	99.66
Nsp7	91.97	97.59	100	100
Nsp8	93.43	98.15	100	100
Nsp9	88.86	98.82	100	100
Nsp10	95.92	98.32	100	100
Nsp12	91.38	97.82	99.46	99.57
Nsp13	92.18	98.06	99.83	99.83
Nsp14	88.56	97.22	98.86	99.24
Nsp15	92	96.24	97.69	97.69
Nsp16	92.51	95.64	100	100
ORF3A	93.24	96.26	97.1	97.83
ORF4/E	99.12	99.56	100	100
ORF5/M	93.62	95.37	98.65	99.55
ORF6	95.7	98.38	96.72	100
ORF7A	93.44	95.63	97.54	97.54
ORF7B	92.42	99.24	95.35	97.67
ORF8	92.08	96.72	94.26	94.26
ORF9/N	96.11	96.83	97.62	98.81
ORF10	99.15	99.15	97.37	97.37
SPIKE	89.17	92.89	highly variable	97.41
average	92.6676	96.916	97.81916667	98.67