Table 2.

Unit costs.

Resource	Unit costs (2015 MXN)A	Sources and assumptions
Vaccine acquisition, cost per dose
Highly effective vaccine	321.00	Mexican Institute of Social Security (IMSS)33
Moderately effective vaccine	289.00	Assumed 10% less than the cost of the highly effective vaccine
Weakly effective vaccine	260.00	Assumed 10% less than the cost of the moderately effective vaccine
Administration costs per dose	18.77	Portnoy et al.34 Incremental cost of any of the three single-dose varicella vaccines administered at the same visit as the measles-mumps-rubella vaccineB
Cost per outpatient visit for varicella	599.00	Unit costs catalog 201535
Cost per prescription medication (for outpatient varicella case)	4.08	Mexican Institute of Social Security (IMSS)33 Cost data assumes the average cost of naproxen 250 mg (30 tablets) and diphenhydramine (60 mL)
Cost per bed day (for inpatient varicella case), by age group
< 1 years	6,054.77	Cost of hospitalization divided by average number of bed days per stay based on Mexican panel of expertsC
1–4 years	6,529.66
5–9 years	6,937.76
10–14 years	6,796.18
15–44 years	5,741.60
45–64 years	5,123.27
≥65 years	4,757.32
Cost per herpes zoster case, by severity
Without postherpetic neuralgia	5,235.33	Rampakakis et al.36
With postherpetic neuralgia	11,290.06

^AWhere necessary, costs were converted and/or adjusted to 2015 MXN using the web-based tool CCEMG – EPPI-Center Cost Converter.³⁷

^BCost of vaccine wastage was excluded because a single-dose vial was assumed to be used.

^CAverage number of bed days per stay based on Mexican panel of experts (Merck & Co., Inc; unpublished). Detailed data shown in Supplemental Table 1.