Table 2. Demographics, operative data and early postoperative course of patients who underwent truncus arteriosus repair (n = 52).
| Variable | All TA repair (n = 52) | Mortality (n = 21) | Survivors in 2018 (n = 31) | p-value |
|---|---|---|---|---|
| Male gender | 25 (48.1%) | 9 (42.9%) | 16 (51.6%) | 0.53 |
| Prenatal diagnosis | 3 (5.7%) | 2 (9.5%) | 1 (3.2%) | 0.55 |
| Age at surgery (days) | 133 (22–6111) | 88 (22–319) | 189 (48–6111) | 0.11 |
| Weight at total repair (kg) | 4.2 (2.2–38.0) | 3.6 (2.2–6.5) | 5.1 (2.9–38.0) | 0.06 |
| Associated anomalies | 18 (34.6%) | 11 (52.4%) | 7 (22.5%) | 0.027* |
| - DiGeorge syndrome | 8 (15.4%) | 4 (19.0%) | 4 (12.9%) | 0.54 |
| TA type I (Collett and Edward) | 37 (71.1%) | 13 (61.9%) | 24 (77.4%) | 0.23 |
| Presence of moderate and severe truncal valve regurgitation | 4 (7.7%) | 3 (14.3%) | 1 (3.2%) | 0.29 |
| Presence of pulmonary artery stenosis | 5 (9.6%) | 3 (14.3%) | 2 (6.5%) | 0.38 |
| Presence of interrupted aortic arch | 1 (1.9%) | 1 (4.7%) | 0 | 0.40 |
| Presence of right side aortic arch | 17 (32.7%) | 7 (33.3%) | 10 (32.6%) | 0.93 |
| Presence of partial anomalous pulmonary venous return | 4 (7.7%) | 0 | 4 (12.9%) | 0.13 |
| Presence of coronary abnormalities | 8 (15.4%) | 4 (19.0%) | 4 (12.9%) | 0.54 |
| Pulmonary artery banding prior to repair | 3 (5.8%) | 1 (4.8%) | 2 (6.5%) | 1.00 |
| Preoperative major infection within 1 month | 10 (19.2%) | 7 (33.3%) | 3 (9.7%) | 0.03* |
| Preoperative being on mechanical ventilator | 2 (3.8%) | 1 (4.8%) | 1 (3.2%) | 1.00 |
| Operative data | ||||
| Surgical era 1999-2006 | 15 (28.8%) | 7 (33.3%) | 8 (25.8%) | 0.55 |
| Cardiopulmonary bypass time (min) | 169.6 ± 43.8 | 181.3 ± 51.1 | 161.7 ± 36.9 | 0.07 |
| Aortic clamp time (min) | 107.2 ± 29.6 | 105.8 ± 26.6 | 108.1 ± 31.9 | 0.79 |
| Truncal valve repaired | 4 (7.7%) | 3 (14.3%) | 1 (3.2%) | 0.14 |
| Aortic arch repaired | 1 (1.9%) | 1 (4.8%) | 0 | 0.22 |
| Conduit size (mm) | 14.2 ± 3.1 | 12.9 ± 2.9 | 15.0 ± 2.9 | 0.01* |
| Conduit size z-score | 2.3 ± 0.9 | 2.3 ± 0.8 | 2.3 ± 1.0 | 0.89 |
| Type of conduit | 0.18 | |||
| - Aortic homograft | 5 (9.6%) | 0 | 5 (16.1%) | |
| - Pulmonary homograft | 10 (19.2%) | 3 (14.3%) | 7 (22.6%) | |
| - Handcock/Carpentier–Edwards valved conduit | 12 (23.1%) | 5 (23.8%) | 7 (22.6%) | |
| - Contegra bovine jugular valved conduit | 24 (46.2%) | 12 (57.1%) | 12 (38.7%) | |
| -Direct anastomosis with monocusp | 1 (1.9%) | 1 (4.8%) | 0 | |
| Intraoperative usage of inhaled nitric oxide | 9 (17.3%) | 6 (28.5%) | 3 (9.6% | 0.07 |
| Early postoperative course | ||||
| Postoperative ECMO | 4 (7.7%) | 4 (19.0%) | 0 | 0.02* |
| Postoperative usage of inhaled nitric oxide | 34 (65.4%) | 16 (76.2%) | 18 (58.1%) | 0.17 |
| Postoperative acute kidney injury requiring renal replacement therapy | 14 (26.9%) | 11 (52.4%) | 3 (9.7%) | 0.001* |
| Postoperative pneumonia | 24 (46.2%) | 8 (38.1%) | 16 (51.6%) | 0.34 |
| Postoperative septicemia | 10 (19.2%) | 6 (28.6%) | 4 (12.9%) | 0.16 |
| Postoperative fatal arrhythmia | 4 (7.7%) | 4 (19.0%0 | 0 | 0.02* |
| Total intensive care unit stay | 8.5 (1–167) | 5 (1–134) | 11 (1–167) | 0.59 |
| Total hospital length of stay | 23 (1–206) | 12 (1–151) | 24 (9–206) | 0.99 |
Notes.
Data represented by median (range), mean ± SD and number (% within column).
Statistically significant at p-value < 0.05 by Chi-square or Fishers exact test and independent T test (for normally distributed data) or Wilcoxon rank-sum test (for non-normally distributed data) TA, truncus arteriosus.
- ECMO
- extracorporeal membrane oxygenator