Table 1.
Different types of vaccines and their developing strategies.
| S.No. | Vaccine type | Pathogen | Disease | Strategy | Reference |
|---|---|---|---|---|---|
| 1. | Multi-epitope based | Kaposi’s sarcoma-associated herpesvirus | Kaposi sarcoma | Immuno-informatics | Chauhan et al., 2019126 |
| 2. | Multi-epitope vaccine | Pseudomonas aeruginosa | Nosocomial infections | Comparative proteomics | Solanki et al., 2019127 |
| 3. | DNA vaccine | Ebola virus | Ebola virus disease | Computer design; gene expression; immunogenicity | Bazhan et al., 2019128 |
| 4. | Multi-epitope Peptide Vaccine | Neisseria gonorrhoeae | Gonorrhea | In-silico hierarchical approach | Jain et al., 2016129 |
| 5. | Subunit vaccine | Marburg virus | Hemorrhagic fever (MHF) | Reverse vaccinology | Hasan et al., 2019130 |
| 6. | Epitope-based | Nairovirus | Crimean-Congo hemorrhagic fever (CCHF) | Molecular docking and dynamics methods | Nosrati et al., 2019131 |
| 7. | Peptide-based vaccine | Providencia stuartii | Purple urine bag syndrome | Reverse Vaccinology (RV) | Asad et al., 2018132 |
| 8. | Multi-epitope vaccine | Human papilloma virus (HPV) | Warts and cancer | Structural vaccinology | Negahdaripour et al., 2018133 |
| 9. | Next generation vaccines | Echinococcus granulosus | Cystic echinococcosis | Systems vaccinology and mathematical/computational modeling | Pourseif et al., 2017134 |
| 10. | Peptide vaccine | Human papillomavirus (HPV) | Cervical cancer | Immunoinformatics and structural vaccinology approaches | Doorbar et al., 2015135 |
| 11. | Multi-epitope peptide vaccine | Brucella spp. | Brucellosis | Immuno-informatics | Saadi et al., 2017136 |
| 12. | Epitope-Based Peptide Vaccine | Mokola Rabies Virus | Meningo-encephalo-myelitis | In silico Approaches | Mohammed et al., 2017137 |
| 13. | T cells with Chimeric Antigen Receptor (CAR) | Acute lymphoblastic leukemia | Acute lymphoblastic leukemia | Genetic engineering | Dokmanović et al., 2017138 |
| 14. | Peptide vaccine | HPV | HPV-associated cancer | Conventional with Immuno-informatics | Atherton et al., 2018139 |
| 15. | Dendritic Cell Vaccines | Cancer antigens | Cancer | Immuno-informatics | Doytchinova et al., 2018140 |
| 16. | DNA Vaccines | Papillomavirus (HPV) | Human Cervical cancer and cervical intraepithelial neoplasia (CIN) | Genetic immuno-therapy, pharmaco-logical tool | Cordeiro et al., 2018141 |
| 17. | Epitopes based | Zika virus | Guillain–Barré syndrome | In silico-predicted immunogenic | Makhluf et al., 2018142 |
| 18. | Epitopes based | Vibrio anguillarum | Vibriosis | Reverse vaccinology | Baliga et al., 2018143 |
| 19. | Multi-epitope subunit vaccine | Chikungunya virus | Chikungunya | Immuno-informatics | Narula, et al., 2018144 |
| 20. | Sub-unit vaccine | Plasmodium falciparum and P. vivax | Malaria | Rational design | Draper et al., 2018145 |
| 21. | Epitope based vaccine | Dengue virus | Dengue | Immuno-informatics and Molecular Docking | Shen et al., 2018146 |
| 22. | Multi-Epitope based vaccine | Staphylococcus aureus | Skin infections and food poisoning | Immuno-informatics and in silico approach | Hajighahramani et al., 2017.147 |