Skip to main content
. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Science. 2020 Apr 10;368(6487):eaaw5473. doi: 10.1126/science.aaw5473

Fig. 1. Intrinsic and extrinsic factors contribute to metabolic phenotypes in tumors.

Fig. 1.

Intrinsic factors include characteristics of the parental tissue as well as new properties arising in the malignant cells as a consequence of altered signaling and transcriptional networks. Extrinsic factors include metabolic stresses imposed by the microenvironment and metabolism of the patient.