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. Author manuscript; available in PMC: 2020 May 15.
Published in final edited form as: Science. 2020 Apr 10;368(6487):eaaw5473. doi: 10.1126/science.aaw5473

Fig. 4. Prospects for using in vivo analysis to match tumor metabolism with metabolic therapies.

Fig. 4.

Several new approaches to assess metabolism in intact tumors, particularly with new imaging approaches, have been used in humans and experimental models to report subtype-selective metabolic properties, some of which correlate with therapeutic sensitivities. MRS, magnetic resonance spectroscopy; D-2HG, D-2-hydroxyglutarate; mIDH, mutant isocitrate dehydrogenase; MCT1, monocarboxylate transporter-1; 18F-BnTP, 4-[18F]fluorobenzy7l-triphenylphosphonium; Gln, glutamine; PET, positron emission tomography; GLS, glutaminase.