Table 6.
Univariate and Multivariate Analysis for Overall Survival in GBC Patients with Age>60 Years
| Univariate Analysis | ||
|---|---|---|
| Characteristics | HR(95% CI) | P value |
| Sex | 1.072 (0.659–1.743) | 0.780 |
| Male | ||
| Female | ||
| Cholecystolithiasis | 1.396 (0.867–2.249) | 0.170 |
| Absent | ||
| Present | ||
| Diabetes | 1.006 (0.594–1.702) | 0.983 |
| Absent | ||
| Present | ||
| Jaundice | 2.279 (1.288–4.033) | 0.005 |
| Absent | ||
| Present | ||
| Blood groups | ———— | 0.091 |
| A | ||
| B | ||
| AB | ||
| O | ||
| Pathological types | 2.999 (0.408–22.046) | 0.281 |
| Adenosquamous carcinoma | ||
| Adenocarcinoma | ||
| Papillocarcinoma | ||
| Degree of differentiation | 1.565 (0.973–2.517) | 0.065 |
| Poor | ||
| Moderate-well | ||
| Resection margin status | 3.627 (2.224–5.917) | <0.001 |
| Negative | ||
| Positive | ||
| Maximum tumor diameter(cm) | 1.015 (0.630–1.635) | 0.951 |
| ≤2.45 | ||
| >2.45 | ||
| T stage | ———— | 0.027 |
| Tis-T1a | ||
| T1b-T2b | ||
| T3 | ||
| T4 | ||
| N stage | ———— | 0.007 |
| 0 | ||
| 1 | ||
| 2 | ||
| Distant metastasis | 2.934 (1.480–5.815) | 0.002 |
| Absent | ||
| Present | ||
| TNM stage | ———— | <0.001 |
| 0-I stage | ||
| IIA-IIB stage | ||
| IIIA-IIIB stage | ||
| IVA-IVB stage | ||
| CA199 | 2.417 (1.431–4.084) | <0.001 |
| ≤39 | ||
| >39 | ||
| LMR | 0.546 (0.337–0.885) | 0.014 |
| ≤4.76 | ||
| >4.76 | ||
| Multivariate Analysis | ||
| Characteristics | HR(95% CI) | P value |
| Resection margin status | 3.299 (1.985–5.483), | <0.001 |
| Negative | ||
| Positive | ||
| Degree of differentiation | 1.726 (1.048–2.843), | 0.032 |
| Poor | ||
| Moderate-well | ||
| Distant metastasis | 3.117 (1.554–6.256), | 0.001 |
| Absent | ||
| Present | ||
| CA199 | 2.137 (1.250–3.651), | 0.005 |
| ≤39 | ||
| >39 | ||
| LMR | ———— | 0.099 |
| ≤4.76 | ||
| >4.76 | ||