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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: J Magn Reson. 2020 Feb 1;312:106691. doi: 10.1016/j.jmr.2020.106691

Table 1:

Compilation of T1 and T2 values calculated in this publication (Meas.) and comparative global/literature values (Global/Lit.). These values are for health Sprague-Dawley rats acquired at 3T. We also added literature values of [1-13C]pyruvate due its widespread use in HP 13C research and clinical trials. These values are strongly reflective of kidney parameter values, particularly T2, and some discrepancies may be due to renal filtration (see discussion).

[1-13C]Pyr [2-13C]Pyr HP001 [13C,14N2]Urea [13C,15N2]Urea
T1 (s) (Meas.) N/A 12.7 35.9 (mean of Fig. 4C, 5C, and 7C) 16.3 17.5
T1 (s) (Global/Lit.) ~30 [43] 13 (Global) 37.1 (Global) 37.9 (mean of Fig. 4D, 5D, and 7F) 32 [36] 19 (Global) 22 (Global)
T2 (s) (Meas.) N/A 1.8 2.3 (mean of Fig. 4E, 5E, and 7D) 0.20 8.6
T2 (s) (Lit.) ~0.6 [33] 0.8 [31] 2.6 (mean of Fig. 4F, 5F, and 7G) ~0.25 [30] See [30] for distributions in kidney