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. Author manuscript; available in PMC: 2021 Mar 4.
Published in final edited form as: ACS Chem Neurosci. 2020 Feb 17;11(5):674–701. doi: 10.1021/acschemneuro.0c00003

Figure 1.

Figure 1.

Figure 1.

A) X-ray crystal structure of 5a (green) which holds a 5’-OH substituent, in the LBD of GluA2 (PDB: 4YMA).38 Receptor surface is displayed in grey. B) X-ray crystal structure of 5a (green) in GluA2 (PDB: 4YMA). Protein surface is colored in grey. The 5’-position directs towards cave-shaped space with a depth of 10–12Å.