Scheme 2. Synthesis of boronic acid 17a.
aReagents and conditions: (a) MeOH, H2SO4, reflux; (b) pinacol, Et2O; (c) LiAlH4, THF, 0–20 °C, (86% over three steps); TBDMSCl, imidazole, DMAP, DMF (quantitative).
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