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. 2020 May 11;12:3301–3310. doi: 10.2147/CMAR.S243490

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© 2020 Li et al.

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(A) Multivariate Cox proportional hazards regression analysis of low-risk CRC patients in stages I–III (N=208). (B) Multivariate Cox proportional hazards regression analysis of high-risk CRC patients in stages I–III (N=209). Multivariables included age at the time of diagnosis, sex, T stage, N stage, anatomical location of primary tumor, adjuvant chemotherapy and mutation status in KRAS and BRAF genes. T stage, N stage were taken as continuous variables into account, while other factors were as categorical variables. Solid tetragonums represent the HR of death, and open-ended horizontal lines represent 95% CIs. All P-values were calculated by using Cox regression analysis.