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. 2020 Apr 28;10:570. doi: 10.3389/fonc.2020.00570

Table 6.

Active combinatorial trials in gastrointestinal cancers.

Trial ID Cancer PARP inhibitor Immunotherapy Phase
NCT02484404 Colorectal Olaparib Atezolizumab (PD-L1) cediranib (VEGFR) I/II
NCT02660034 •HER2-negative gastric •Gastroesophageal junction •Advanced pancreatic BGB-290 BGB-A317 (PD-1) I/II
NCT03851614 •Advanced pancreatic •dMMR colorectal Olaparib Durvalumab (PD-1) I/II
NCT03404960 Advanced pancreatic Niraparib Nivolumab (PD-1) ipilimumab (CTLA-4) I/II
NCT03637491 Advanced pancreatic Talazoparib Avelumab (PD-1) I/II
NCT02734004 Relapsed gastric Olaparib Durvalumab (PD-L1) +/− bevacizumab I/II
NCT03639935 Biliary Rucaparib Nivolumab (PD-1) II