Table 1:
Baseline patient characteristics (n = 50)
| Patient Characteristic | No. (%) or Median (Range) |
|---|---|
| No. of MR imaging studies | 50 (100) |
| Sex | |
| Male | 24 (48) |
| Female | 26 (52) |
| Median age at registration (range) (yr) | 6 (3.3–17.5) |
| Molecular subgroups | |
| MGMT–/EGFR– | 28/48 (58) |
| MGMT–/EGFR+ | 14/48 (29) |
| MGMT +/EGFR– | 3/48 (6) |
| MGMT +/EGFR+ | 3/48 (6) |
| Unassigned | 2 |
| Mutational statusa | |
| Any histone mutation | 34/49 (69) |
| Wild-type | 15/49 (31) |
| Histone mutation (among patients with any histone mutations)a | |
| H3F3A | 23/34 (68) |
| HIST1H3B | 8/34 (24) |
| HIST1H3C | 3/34 (9) |
| Median follow-up time (range) (mo) | 10.9 (0.4–33.4) |
a
One patient with both H3F3A and HIST1H3B histone mutations was excluded.