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Vaccines (and particularly adjuvanted vaccines) have an optimum storage temperature that is usually between 2 and 8°C (domestic refrigerators should be maintained at 4°C). These products should not be frozen or positioned adjacent to the freezer compartment of the refrigerator, and refrigerator temperature should be monitored regularly by use of a maximum–minimum thermometer located in the main body of the refrigerator. Ideally, the temperature of the refrigerator should be charted in a log book on a daily basis
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Freeze‐dried vaccines should be reconstituted immediately before use with appropriate diluent or liquid vaccine given concurrently (as per manufacturer's recommendations). It is bad practice and contraindicated to make up first thing in the morning the vaccines anticipated to be used during the day. Some vaccine components (e.g. CDV, FHV‐1) are particularly labile in this regard and so these vaccines may not induce adequate immunity if not reconstituted just before use
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