Table 2.
Association of patterns of pulmonary disease with specific histologic features observed in dairy cows with bovine respiratory disease
| Pulmonary patterns | Agent | Associated features |
|---|---|---|
| Interstitial pneumonia (n = 15) |
BVDV BoHV‐1 BRSV BPIV‐3 |
Necrotizing bronchitis Necrotizing bronchiolitis Necrohemorrhagic bronchitis with angiogenesis Syncytial formation Ballooning degeneration of bronchial/bronchiolar epithelium Hyperplasia of type II pneumocytes |
| Necrosuppurative bronchopneumonia (n = 9) | M. bovis | Accumulations of intralesional Giemsa‐stained coccoid bacteria |
| Peribronchial lymphocytic cuffings | ||
| Suppurative bronchopneumonia (n = 6) | M. bovis | Accumulations of intralesional Giemsa‐stained coccoid bacteria |
| Peribronchial lymphocytic cuffings | ||
| Without pneumonia (n = 2) | BRSV | Necrotizing bronchitis |
Abbreviations: BoHV‐1: bovine alphaherpesvirus type 1; BPIV‐3: bovine parainfluenza virus type 3; BRSV: bovine respiratory syncytial virus; BVDV: bovine viral diarrhea virus; and M. bovis: Mycoplasma bovis.