Table 3.
Principal histopathologic diagnosis/features and immunohistochemical findings of bovine respiratory disease in 32 dairy cows
| Histopathologic diagnosis/features | Detection of pathogens in the lungs (number/total) |
|---|---|
| Obliterative bronchiolitis | M. bovis (10/10) |
| Accumulations of intralesional Giemsa‐stained coccoid bacteria | M. bovis (9/9) |
| Necrosuppurative bronchopneumonia | M. bovis (9/9) |
| Peribronchial lymphocytic cuffings | M. bovis (8/8) |
| Suppurative bronchopneumonia | M. bovis (6/6) |
| Interstitial pneumonia | BVDV (10/15) |
| BoHV‐1 (9/15) | |
| BRSV (4/15) | |
| BPIV‐3 (1/15) | |
| Necrotizing bronchitis | BVDV (4/6) |
| BRSV (4/6) | |
| BoHV‐1 (2/6) | |
| Necrotizing bronchiolitis | BVDV (4/4) |
| BRSV (2/4) | |
| Necrohemorrhagic bronchitis with bronchial angiogenesis | BoHV‐1 (2/2) |
| Syncytial formation | BRSV (4/4) |
| Ballooning degeneration of bronchial epithelium | BoHV‐1 (2/3) |
| BRSV (1/3) | |
| Hyperplasia of type II pneumocytes | BRSV (2/2) |
| Ballooning degeneration of bronchial epithelium of bronchiolar epithelium | BoHV‐1 (1/1) |
Abbreviations: BoHV‐1: bovine alphaherpesvirus type 1; BPIV‐3: bovine parainfluenza virus type 3; BRSV: bovine respiratory syncytial virus; BVDV: bovine viral diarrhea virus; M. bovis: Mycoplasma bovis.