Table 5.
Association of principal histopathologic patterns/features and positive immunoreactivity with infectious disease agents of bovine respiratory disease in dairy cows
| Histopathologic patterns/features | Positive immunoreactivity | ||||
|---|---|---|---|---|---|
| M. bovis | BVDV | BoHV‐1 | BRSV | BPIV‐3 | |
| Necrossupurative and suppurative bronchopneumonia | X | ||||
| Obliterative bronchiolitis | X | ||||
| Peribronchial lymphocytic cuffings | X | ||||
| Bronchial angiogenesis | X | ||||
| Ballooning degeneration of bronchial, bronchiolar and alveolar epithelium | X | X | |||
| Necrotizing bronchitis and bronchiolitis | X | X | X | ||
| Necrohemorrhagic bronchitis | X | X | |||
| Hyaline cartilage of the bronchus | X | X | X | X | |
| Mixed peribronchial glands | X | X | X | ||
| Syncytial formation | X | ||||
| Interstitial pneumonia | X | X | X | X | |
Abbreviations: BoHV‐1, bovine alphaherpesvirus type 1; BPIV‐3, bovine parainfluenza virus type 3; BRSV, bovine respiratory syncytial virus; BVDV, bovine viral diarrhea virus; M. bovis, Mycoplasma bovis.