Glucose clearance after IPGTT. The blood glucose levels after a glucose bolus at 4 (A) and 8 (B) weeks after islet transplantation. The glucose clearance from the blood expressed as AUC (mg/dL per minute) for HC mice, DC mice, and the 800 and 1200 islets groups of the kidney capsule and the scaffold. The clearance was measured 4 and 8 weeks after islet transplantation (C). Median and interquartile range are plotted (n = 5), a statistical analysis was carried out using a 2-way ANOVA with a Bonferroni post hoc test (P < 0.05). (a) significantly different compared to the HC, (b) significantly different compared to the DC, (c) significantly different compared to the 1200 islets transplanted under the kidney capsule of the same time point.