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. 2017 Apr 25;101(4):764–777. doi: 10.1097/TP.0000000000001420

FIGURE 8.

FIGURE 8.

A, Density of HLA-I conformational variants on SAB and T-cells. HLA-I beads has highest density of pepA-β2aHC followed by pepF-β2aHC and then low density of β2fHC. iBeads has highest density of pepA-β2aHC and low density pepF-β2aHC and minimal density of β2fHC. Acid/Alkali-treated beads only bear β2fHC. T-cells only bear pepA-β2aHC. B, HLA-I conformational variants recognized by the mAbs. W6/32 recognize both pepA-β2aHC and pepF-β2aHC. HC-10 recognize pepF-β2aHC and pepF-β2fHC. TFL-006 recognize pepF-β2fHC and possibly pepA-β2fHC.