Table 1.
Main physical chemistry properties of the studied proteins. Protein net charge numbers (Z) for the investigated proteins at physiological ionic strength (150 mM) and two different pH solution conditions (4.6 and 7.0). The macromolecular area (A) is given in Å2 as calculated by “UCSF Chimera” package. (Pettersen et al., 2004).
| pH | RBD SARS-CoV-1 | RBD SARS-CoV-2 | 80R | CR3022 | m396 | F26G19 | ACE2 |
|---|---|---|---|---|---|---|---|
| 4.6 | 5.2 | 5.5 | 9.1 | 4.2 | 2.7 | 5.8 | 5.4 |
| 7.0 | 2.0 | 2.2 | 5.1 | 1.0 | −2.6 | 0.1 | −23.0 |
| A | 8889 | 9079 | 9767 | 9831 | 5362 | 10,120 | 25,290 |