Table 2.
Genome single nucleotide polymorphisms compared with reference sequence
|
Gene and position* |
GenBank accession number |
||||||
|---|---|---|---|---|---|---|---|
| Non-coding gene, position 241 |
ORF1ab |
S |
|||||
| Position 3037 | Position 6446 | Position 9891 | Position 22323 | Position 23403 | |||
| Nucleotide in reference | C | C | G | C | C | A | .. |
| Patient 1 | T | T | G | C | C | G (Asp>Gly) | MT270101 |
| Patient 2 | T | T | G | C | C | G (Asp>Gly) | MT270112 |
| Patient 3 | T | T | G | C | C | G (Asp>Gly) | MT270103 |
| Patient 4 | T | T | A (Val>Ile) or G | Y (for T, Ala>Val) | C | G (Asp>Gly) | MT270102 |
| Patient 5 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270105 |
| Patient 6 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270104 |
| Patient 7 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270106 |
| Patient 8 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270107 |
| Patient 9 | T | T | A (Val>Ile) | C | T (Ser>Phe) | G (Asp>Gly) | MT270108 |
| Patient 10 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270110 |
| Patient 11 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270109 |
| Patient 14 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270111 |
| Patient 16 | T | T | A (Val>Ile) | C | C | G (Asp>Gly) | MT270113 |
No specimens were available for sequencing for patients 12, 13, and 15. A=adenine. G=guanine, T=thymine. C=cytosine.
*
Positions relative to EPI_ISL_402125 (the genome with closest similarity presently available on GISAID). Information in parentheses are amino acid exchanges in case of non-silent mutations.