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. 2020 May 15;6(20):eaba4311. doi: 10.1126/sciadv.aba4311

Fig. 2. Alga-gel activates cells against hypoxia and high glucose in vitro.

Fig. 2

(A) Illustration of the wound-healing process and design scheme with alga-gel. (B and C) Alga-gel reduced HIF-1α on high glucose–induced HSF (n = 3). Scale bars, 200 μm. (D and E) HSF cell proliferation with 33 mM glucose and 6 hours of hypoxia in different groups (n = 3). Scale bars, 200 μm. (F and G) Representative images and quantification of HaCaT cell migration (n = 3). Scale bars, 100 μm. (H and I) Representative images and quantitative analysis of transwell migration assay in HUVECs (n = 3). Scale bars, 200 μm. (J and K) Representative images and quantification of HUVECs’ tube formation (n = 3). Scale bars, 200 μm. Significantly different (one-way ANOVA): *P < 0.05, **P < 0.01, and ***P < 0.001.