Table 1.
Study Characteristics
| Study (Year) | Size Sample | Age | % Male | Substance Type | Type of SOIT | Type of individual tx | Tx length difference | Substance use measure | Time-point | RoB | Relationship to significant-other involved |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Azrin et al. (2001) | 56 | 15.40 | 82.14 | CMD | Family (Other-SOIT) | CBT | 0 | Freq | PT FU (6 mo.) | Unclear | Caregiver |
| Dennis et al. (2004) | 300 | N/R | 81.33 | CMD | Family (MDFT) CRA | MET | 9.5 | Abs | FU (9 mo.) | Unclear | Caregiver |
| Hedberg & Campbell (1974) | 49 | 38.20 | 91.84 | AUD | Family (Other-SOIT) | OIACT | 0 | Other | PT | High | Partner |
| Liddle et al. (2008) | 224 | 15.40 | 81.25 | CMD | Family (MDFT) | CBT | 0 | Freq Prob | PT FU (12 mo.) | Unclear | Caregiver |
| Liddle et al. (2018) | 113 | 15.36 | 75.00 | CMD | Family (MDFT) | MET | 0 | Freq Prob | FU (12 mo.) | Unclear | Caregiver |
| McCrady et al. (2009) | 102 | 45.05 | 0.00 | AUD | Couple (BCT) | CBT | 0 | Abs Other | PT FU (12 mo.) | Low | Partner |
| O’Farrell et al. (2010) | 29 | 29.09 | 55.17 | CMD | Family (Other-SOIT) | CBT | 0 | Abs Freq Prob | PT FU (6 mo.) | Unclear | Other |
| O’Farrell et al. (2017) | 61 | 38.70 | 0.00 | CMD | Couple (BCT) | 12-step | 0 | Abs Freq Prob | PT FU (12 mo.) | Low | Partner |
| Rigter et al. (2013) | 450 | 16.30 | 85.00 | CMD | Family (MDFT) | CBT | N/R | Freq | PT FU (6 mo.) | Unclear | Caregiver |
| Schumm et al. (2014) | 105 | 44.40 | 0.00 | CMD | Couple (BCT) | 12-step | 0 | Abs Prob | PT FU (12 mo.) | Unclear | Partner |
| Slesnick & Prestopnik (2009) | 119 | 15.13 | 45.38 | CMD | Family (FFT) Family (EBFT) | OIACT | N/R | Freq Quant Prob | PT FU (12 mo.) | Unclear | Caregiver |
| Slesnick et al. (2013) | 179 | 15.40 | 47.49 | CMD | Family (EBFT) | OIACT | 5 | Freq | PT FU (18 mo.) | Unclear | Caregiver |
| Vedel et al. (2008) | 64 | 45.50 | 85.94 | AUD | Couple (BCT) | CBT | 0 | Quant | PT FU (6 mo.) | Unclear | Partner |
| Waldron et al. (2001) | 120 | 15.61 | 80.00 | DUD (marijuana) | Family (FFT) Family (Joint FFT/CBT) | MET | 6 | Freq | PT FU (3 mo.) | Unclear | Caregiver |
| Walker (2001) | 25 | 34.00 | 54.64 | DUD (stimulants) | CRA | OIACT | 0 | Abs | PT FU (3 mo.) | Low | Other |
| Yandoli et al. (2002) | 119 | 28.20 | 63.00 | DUD (opiates) | Family (Other-SOIT) | OIACT | N/R | Other | PT | High | Other |
Note. SOIT= Significant-Other Involved Treatment; AUD= Alcohol Use Disorder; CMD= Combined alcohol and drug use disorder, with specific drug-type varying within sample; DUD= Drug Use Disorder; CRA= Community Reinforcement Approach; BCT= Behavioral Couple Therapy; EBFT= Ecologically Based Family Therapy; FFT= Functional Family Therapy; MDFT= Multidimensional Family Therapy; Other-SOIT= Other Significant-Other Involved Treatment; CBT= Cognitive Behavioral Therapy; MET= Motivational Enhancement Treatment; 12-step= 12-step focused individual treatment; OIACT= Other Individual Active Comparator Treatment; Freq= Frequency; Quant= Quantity; Prob= Problems; Abs= Abstinence; PT= Post -Treatment; FU= Follow-up; mo.= month; Tx= Treatment; N/R: information Not/Reported; RoB= Risk of Bias. Of note, the treatment length difference was computed as the total number of sessions required for SOIT subtracted from the total number of sessions for individually-based active comparator treatments.