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. 2020 May 16;159(3):1170–1172.e1. doi: 10.1053/j.gastro.2020.05.034

Supplementary Table 1.

Characteristics of Patients With COVID-19 With Hypertension in the ACEI/ARB and Non-ACEI/ARB Groups

Characteristics ACEI/ARB group (n = 31) Non-ACEI/ARB group (n = 69) P
Sex (male: female) 14:17 37:32 .285
Age, median (IQR) 67 (62–70) 67.5 (57–71) .479
Duration, median (IQR) 10(7–16.5) 12 (8.8–16) .041
Respiratory symptoms, n (%) 20 (64.5) 48 (69.6) .359
 Fever 24 (77.4) 53 (76.8) .850
 Cough/expectoration 15 (48.4) 37 (53.6) .528
 Shortness of breath 5 (16.1) 24 (34.8) .047
 Chest distress 3 (9.7) 5 (7.2) .710
GI symptoms, n (%) 4 (12.9) 20 (29) .082
 Diarrhea 2 (6.5) 10 (14.5) .211
 Vomiting 3 (9.7) 8 (11.6) .738
 Abdominal pain 2 (2.9) 2 (6.5) .436
Comorbidities on admission, n (%)
 Diabetes 8 (25.8) 20 (29) .616
 GI comorbidities 6 (19.4) 17 (24.6) .513
 Chronic renal diseases 4 (12.9) 5 (7.2) .398
 Coronary heart disease 5 (16.1) 13 (18.8) .697
 COPD 2 (6.5) 7 (10.1) .524
 Tumor 1(3.2) 4(5.8) .566
Laboratory examination on admission, median (IQR)
 AST 27.5 (24-30.75) 31.5 (22-49) .103
 ALT 34 (20-48) 32 (18-59.7) .409
 TBIL 11.6 (7.8-13.9) 11.4 (7.4-17.1) .153
 CRP 23.97 (4-43) 24 (6.7-62.5) .406
 Lymphocyte 1.16 (0.8-1.6) 1.01 (0.73-1.3) .109
 D-dimer 0.76 (0.26-2.39) 0.96 (0.58-2.1) .609
Severity, n (%) .613
 Mild 0 (0) 2 (2.9)
 Moderate 4 (12.9) 7 (10.1)
 Severe 24 (77.4) 38 (55.1)
 Critical 3 (9.7) 22 (31.9)
In-hospital management, n (%)
 Antiviral drug 19 (61.3) 52 (75.4) .093
 Antibiotic drug 17 (54.8) 40 (58) .650
 Antifungal medications 0 4 (5.8) .077
 Systemic corticosteroids 3 (9.7) 26 (37.7) .003
 Lipid-lowering drug 8 (25.8) 10 (14.5) .196
 CCB 15 (48.4) 24 (34.8) .237
 Beta-blocker 10 (32.3) 3 (4.3) <.001
 Alpha-blocker 1 (3.2) 1 (1.4) .573
 ACEI 4 (12.9) 0
 ARB 27 (87.1) 0
 Renal replacement therapy 1 (3.2) 5 (7.2) .416
 Noninvasive ventilation 0 5 (7.2) .048
 Invasive ventilation 2 (6.5) 9 (13) .287

NOTE. Bold values are time from onset to admission, days, median (IQR).

ALT, alanine aminotransferase; AST, aspartate transaminase; CCB, calcium channel blockers; COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; IQR, Interquartile range; TBIL, total bilirubin.