Table 1.
Characteristics of two IgG4-RD patients with COVID-19.
| Basic information | Patient 1 | Patient 2 | The last follow-up | Patient 1 | Patient 2 |
|---|---|---|---|---|---|
| Age (y) | 58 | 45 | IgG4 (g/L) | 11.4 | 4.19 |
| Gender | Male | Male | T-IgE (<100) | 477.9 | 14.65 |
| History of IgG4-RD (y) | 2 | 1.5 | CD3+CD19-(955-2860) | 985 | 966 |
| IgG4-RD RI (the first follow up) | 18 | 15 | CD3+CD8+(320-1250) | 209 | 271 |
| IgG4-RD RI (the last follow up) | 1 | 6 | CD3+CD4+ (550-1440) | 744 | 634 |
| Biological agents | No | No | CD3-CD19+ (90-560) | 127 | 149 |
| Prednisone (mg/d) | 5 | 5 | NK (150-1100) | 1473 | 1423 |
| Symptoms | Comorbidities | ||||
| Fever | Yes | Yes | Hypertension | No | No |
| Cough | Yes | Yes | Cardiovascular disease | No | No |
| Fatigue | Yes | Yes | Diabetes | Yes | No |
| Diarrhea | No | No | Tumor | No | No |
| Lab findings | Complications | ||||
| PT, s (10-16) | 13.5 | 15.4 | ARDS | No | No |
| D-dimer, mg/L (0-0.5) | 0.58 | 0.16 | Shock | No | No |
| Albumin, g/L (40-55) | 33.1 | 42.3 | Acute cardiac injure | No | No |
| ALT, U/L (9-50) | 118 | 77 | Acute liver injure | Yes | Yes |
| AST, U/L (15-40) | 36 | 36 | Acute kidney injure | No | No |
| LDH, U/L (120-250) | 330 | 66.1 | Electrolyte disorder | Yes | Yes |
Abbreviations: PT, prothrombin time, ALT, alanine aminotransferase, LDH, lactic dehydrogenase, AST, aspartate transaminase, ARDS, acute respiratory distress syndrome, IgG4-RD, IgG4 related disease.