Table 3.
Distribution and association LPA SNPs with Lp(a) concentrations
| SNP | n (%) | Mean Lp(a) | Median Lp(a) | p value |
|---|---|---|---|---|
| rs10455872 | ||||
| Wild-type (AA) | 1514 (87.6%) | 20.95 (35.01) | 9.00 (4.00–20.30) | 2.35 × 10−86 |
| Heterozygous (AG) | 202 (11.7%) | 70.58 (52.21) | 62.00 (47.00–78.50) | |
| Homozygous (GG) | 11 (0.7%) | 158.76 (62.12) | 167.00 (96.90–203.00) | |
| rs3798220 | ||||
| Wild-type (TT) | 1644 (96.9%) | 25.23 (37.12) | 11.00 (5.00–30.00) | 4.33 × 10−31 |
| Heterozygous (TC) | 51 (3%) | 94.04 (97.88) | 74.95 (7.25–155.50) | |
| Homozygousa (CC) | 1 (0.1%) | 74.00 (NA) | NA | |
Mean (± SD), median (IQR) are given
an = 1, SD not applicable (NA)