Table 2.
Changes in adipokines, inflammatory cytokines and markers of oxidative stress
| Baseline | 1 month | 6 months | 4 years | p | |
|---|---|---|---|---|---|
| Adiponectin* (ng/mL) | 8.3 (5.3–10.5) | 7.7 (4.0–12.2) | 8.2 (4.6–12.1) | 6.3 (4.7–13.3) | 0.937 |
| Leptin* (pg/mL) | 60.7 (32.3–70.3) | 40.4 (23.1–62.8) | 33.7 (15.6–51.7) | 32.1 (15.4–45.7) | 0.001 |
| CRP* (ng/mL) | 11.4 (3.5–33.0) | 3.7 (1.9–19.3) | 5.8 (1.9–32.1) | 2.8 (1.5–5.7) | 0.006 |
| IL-6* (pg/mL) | 8.0 (4.2–16.7) | 5.6 (3.8–23.3) | 11.7 (5.1–24.9) | 2.1 (0.9–5.4) | 0.005 |
| IL-10* (pg/mL) | 7.2 (2.5–9.3) | 6.4 (4.9–9.4) | 7.1 (5.2–9.4) | 5.1 (3.9–8.4) | 0.140 |
| Fasting TBARS1 (ng/mL) | 44 ± 29 | 24 ± 16 | 26 ± 8 | 63 ± 20 | 0.388 |
| 120-min TBARS2 (ng/mL) | 74 ± 41 | 49 ± 24 | 43 ± 24 | 72 ± 24 | 0.157 |
| Fasting TAOS (%) | 38.3 ± 10.8 | 35.5 ± 9.1 | 36.3 ± 8.5 | 51.6 ± 17.2 | 0.042 |
| 120-min TAOS (%) | 40.9 ± 7.6 | 39.4 ± 9.3 | 33.6 ± 10.8 | 48.5 ± 13.5 | 0.026 |
*Data are presented as median and interquartile range. Data are presented as mean and SD. 1Nine outliers excluded from analysis. 2Eight outliers excluded from the analysis. p value calculated from ANOVA or Friedman test