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. 2020 May 15;10:8013. doi: 10.1038/s41598-020-64975-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Sequence preference for cytosine DNA methylation. Weblogo analysis of bases surrounding mC sites within different sequence contexts. The X axis represents the position of bases in which the methylated cytosine is placed in the fourth position. The Y axis indicates the entropy of the base. (A), (B) and (C) represent CG, CHG and CHH sequence contexts, respectively. Further, a and b represent all C sites and mC sites, respectively.