Table 2.
Model | HR (95% CI) per year decrease | |
---|---|---|
Early type 2 diabetes | Late type 2 diabetes | |
Base model | 1.28 (1.21, 1.36) | 1.13 (1.06, 1.19) |
+ Adjustment for cBMI | 1.24 (1.17, 1.31) | 1.11 (1.05, 1.17) |
+ Adjustment for aBMI | 1.15 (1.08, 1.22) | 1.05 (0.99, 1.11) |
+ Adjustment for cBMI and aBMI | 1.16 (1.09, 1.23) | 1.05 (0.99, 1.11) |
HRs (95% CI) per year decrease in age at PHV were calculated using Cox proportional hazards regression. Number of early (occurring ≤57.2 years) type 2 diabetes cases n = 926; total number in analysis n = 30,697. Number of late (occurring >57.2 years) type 2 diabetes cases n = 925, total number in analysis n = 24,513. All models are adjusted for birth year and country of birth with or without further adjustment for childhood BMI (at 8 years of age), young adult BMI (at 20 years of age), or both childhood BMI and young adult BMI
aBMI, young adult BMI; cBMI, childhood BMI