Table 2.
Summary of TAms discovered using metagenomic approaches
| Enzyme | (S)/(R) | Comments | Reference |
|---|---|---|---|
| Sequence-driven approach | |||
| pQR1108–pQR1118 | (S) | Metagenome derived from oral cavities of humans | Baud et al. (2017) |
| Is3-TA | (S) | Metagenome derived from hot spring metagenomes in Italy and Iceland | Ferrandi et al. (2017) |
| It6-TA | (S) | ||
| B3-TA | (S) | ||
| pQR2188–pQR2191 | (S) | Metagenome derived from DNA isolated from domestic drain | Leipold et al. (2019) |
| pQR2193 | (S) | ||
| pQR2200–pQR2202 | (S) | ||
| pQR2204–pQR2209 | (S) | ||
| pQR2211 | (S) | ||
| pQR2213–pQR2213 | (S) | ||
| KMG-TAm4 | (S) | Metagenome derived from Triassic period salt mine | Kelly et al. (2018a, b) |
| Functional metagenomics | |||
| pRT15-TA | (S) |
Fosmid library generated for screening Sequence 15% shorter than Vf-TAm and Cv-TAm |
Pawar et al. (2018) |
| TR1 to TR10 | (S)a | Fosmid library | Coscolín et al. (2019) |
| Metagenomic derived from 28 geographically distinct environments, including chronically polluted marine sediment samples, an acidic beach pool and the genome of Pseudomonas oleovorans | |||
aEnzymes TR2, TR6, TR9, and TR10 accepted both enantiomers of 2-aminononane