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. 2020 May 15;11:2446. doi: 10.1038/s41467-020-16175-y

Table 1.

Various light-inducible systems developed since 2012.

Light DBD A/RD Photoreceptor and partner Host Reference
Blue ZFP VP16 AD LOV and GI Human cell Polstein et al.109
Red TALE VP64 AD Cry2 and CIB1 Mammalian cell Konermann et al.110
Red Gal4 VP16 AD PhyB and PIF3 Mammalian cell Müller et al.111
UV-B UVR8 and COP1
Blue LOVpep and PDZ
Red TetR VP16 AD PhyB and PIF3 Plant cell Müller et al.112
Blue CRISPR/Cas9 VP64 AD Cry2 and CIB1 Mammalian cell Polstein et al.113
Blue CRISPR/Cas9 P65 AD Cry2 and CIB1 Mammalian cell Nihongaki et al.114
Blue LexA VP16 AD Cry2 and CIB1 S. cerevisiae Taslimi et al.115
Red TALE VP64 AD PhyB and PIF3 S. cerevisiae Hochrein et al.53
Red TALE VP64 AD PhyB and PIF3 S. cerevisiae Hochrein et al.57
Blue N terminal-T7 RNAPs C terminal-T7 RNAPs AD nMag and pMag E. coli Baumschlager et al.116
Blue LexA Gal4 AD ClpX and ClpP S. cerevisiae Xu et al.117
Blue Gal4 Gal4 AD WC-1 and VVD S. cerevisiae Salinas et al.118
Blue TetR P65 AD Cry2 and CIB1 Plant cell Yamada et al.119
Green AdoB12 VP16 AD CarH and CarO Plant cell Mammalian cell Chatelle et al.52
Blue ZFP VP16 AD CRY2 and CIB1 S. cerevisiae An-adirekkun et al.120
Blue NLS dCas9 RD LOV and α helix S. cerevisiae Geller et al.121