Table 3.
Transthoracic echocardiography in the safety-evaluation group, performed on baseline (day zero) and follow-up (day seven). Left ventricular ejection fraction (LVEF) was not deteriorated. There was no overall thickening of the septal wall, measured in short axis view. There was no measurable pericardial effusion (Pex), aortic regurgitation (AR) or mitral regurgitation (MR).
| Animal ID | Timepoint | LVEF (%) | Wall thickness (mm) | Pex | AR | MR |
|---|---|---|---|---|---|---|
| 1 | Baseline | 59 | 8 | 0 | 0 | 0 |
| Follow-up | 65 | 9 | 0 | 0 | 0 | |
| 2 | Baseline | 66 | 10 | 0 | 0 | 0 |
| Follow-up | 72 | 9 | 0 | 0 | 0 | |
| 3 | Baseline | 55 | 8 | 0 | 0 | 0 |
| Follow-up | 72 | 6 | 0 | 0 | 0 |