Table 4.

Interval changes of the LANSS, VAS-N, VAS-A, NDI, and EQ-5D scores after the first 4 weeks and during the next 4 weeks.

	Opioid-only group	Pregabalin add-on group	p-value
LANSS
From baseline to 4 weeks	2.9 ± 3.5	6.2 ± 2.8	0.005
From 4 weeks to 8 weeks	2.4 ± 4.0	3.3 ± 2.5	0.615
VAS-N
From baseline to 4 weeks	2.8 ± 1.7	4.7 ± 1.6	0.001
From 4 weeks to 8 weeks	1.8 ± 1.3	2.2 ± 1.0	0.377
VAS-A
From baseline to 4 weeks	2.8 ± 1.5	4.1 ± 1.6	0.035
From 4 weeks to 8 weeks	1.9 ± 1.9	1.7 ± 1.5	0.716
NDI
From baseline to 4 weeks	4.1 ± 8.7	5.5 ± 6.8	0.847
From 4 weeks to 8 weeks	3.3 ± 6.7	2.3 ± 5.9	0.279
EQ-5D
From baseline to 4 weeks	0.11 ± 0.14	0.08 ± 0.14	0.645
From 4 weeks to 8 weeks	0.09 ± 0.08	0.06 ± 0.12	0.765

Abbreviations: LANSS, Leeds assessment of neuropathic symptoms and signs; VAS-N, visual analogue scale for neck pain; VAS-A, visual analogue scale for arm pain; NDI, neck disability index; EQ-5D, EuroQol-5Dimension.

The values represent the means ± the standard deviations. Boldface type indicates statistical significance.