Table 6.

Differences in metabolism between the MAGs and cultured isolate genomes.

Metabolism	Caminicella sporogenes	Paramaledivibacter caminithermalis	A2 P. tenebris MAG	B6 P. tenebris MAG	B7 P. tenebris MAG	B9 P. tenebris MAG
Wood-Ljundahl Pathway
Complete pathway			X	X	X
Sulfur metabolism
Anaerobic Sulfite Reductase			X	X	X	X
Aden-5’phosphosulfate Reduct			X	X	X	X
Sulfite reductase(ferrodoxin)			X	X	X	X
Butanoate Metabolism
Pyruvate <–> Acetyl CoA	X	X	X	X	X	X
Acetyl CoA <–> AcetoacetylCoA	X	X	X	X	X	X
Acetyl CoA < –> Butanoate	X	X	X	X	X	X
Acetyl CoA <–> Butanol	X	X	X	X	X	X
Starch and Sucrose
Extracellular Cellubiose	X	X
Starch/Glycogen–> Glucose		X	X	X	X	X
Sucrose–> Glucose			X	X	X	X
Membrane Transport
Phosphonate			X	X	X	X
Liposaccharide			X	X		X
Glycine betaine/proline			X	X	X	X
Cobalt			X	X	X	X
Nickel			X	X	X	X
Galactitol			X	X	X	X
Mannitol			X	X	X	X
Sorbital			X	X	X	X
Sucrose			X	X	X	X
Amino Acid	X	X
Branched Chain Amino Acids		X
Bacitracin/Lantibiotics		X
Cellubiose/diacetylchitobiose	X	X
Complete D-xylose		X
Galactose oligomer	X
N-acetyl-D-glucosamine	X	X
Two-component systems
Temperature	X	X	X	X	X	X
Salt Stress	X	X	X	X	X	X
Chemotaxis	X	X	X	X	X	X
Flagella regulon genes	X	X	X	X	X	X
Tricarboxylate transport	X	X
Citrate formation genes		X	X	X	X	X