Table 2.
List of proteins modulates with the function of gestational age.
| UniProt Id | Protein Name | Gene Name | FC(V2/V1) | FC(V3/V1) | FC(V3/V2) | p_values | q_values | Cluster |
|---|---|---|---|---|---|---|---|---|
| Q562R1 | Beta-actin-like protein 2 | ACTBL2 | 0.52 | 1.17 | 2.24 | 0.014 | 0.055 | 1 |
| P43652 | Afamin | AFM | 1.29 | 2.02 | 1.56 | 0.000 | 0.000 | 1 |
| P13716 | Delta-aminolevulinic acid dehydratase | ALAD | 0.78 | 1.19 | 1.53 | 0.022 | 0.078 | 1 |
| P04075 | Fructose-bisphosphate aldolase A | ALDOA | 1.04 | 2.20 | 2.12 | 0.005 | 0.023 | 1 |
| P19961 | Alpha-amylase 2B | AMY2B | 0.50 | 2.67 | 5.30 | 0.000 | 0.000 | 1 |
| P01024 | Complement C3 | C3 | 0.72 | 1.10 | 1.52 | 0.011 | 0.045 | 1 |
| P27797 | Calreticulin | CALR | 0.50 | 0.75 | 1.49 | 0.016 | 0.058 | 1 |
| P08571 | Monocyte differentiation antigen CD14 | CD14 | 0.37 | 0.29 | 0.78 | 0.000 | 0.000 | 1 |
| Q9NYQ6 | Cadherin EGF LAG seven-pass G-type receptor 1 | CELSR1 | 0.56 | 1.00 | 1.77 | 0.019 | 0.067 | 1 |
| Q14019 | Coactosin-like protein | COTL1 | 0.65 | 1.74 | 2.68 | 0.002 | 0.011 | 1 |
| P00450 | Ceruloplasmin | CP | 0.73 | 1.10 | 1.50 | 0.005 | 0.022 | 1 |
| P07339 | Cathepsin D | CTSD | 0.42 | 1.00 | 2.37 | 0.002 | 0.008 | 1 |
| P81605 | Dermcidin | DCD | 0.56 | 1.15 | 2.03 | 0.012 | 0.046 | 1 |
| P06733 | Alpha-enolase | ENO1 | 0.67 | 1.43 | 2.14 | 0.003 | 0.013 | 1 |
| P09104 | Gamma-enolase | ENO2 | 0.68 | 1.21 | 1.78 | 0.000 | 0.002 | 1 |
| P84090 | Enhancer of rudimentary homolog | ERH | 1.61 | 3.13 | 1.94 | 0.000 | 0.000 | 1 |
| Q8N0U4 | Protein FAM185A | FAM185A | 0.72 | 1.06 | 1.47 | 0.021 | 0.075 | 1 |
| P78417 | Glutathione S-transferase omega-1 | GSTO1 | 0.48 | 1.20 | 2.49 | 0.000 | 0.002 | 1 |
| P16402 | Histone H1.3 | HIST1H1D | 1.32 | 3.84 | 2.92 | 0.007 | 0.030 | 1 |
| P11142 | Heat shock cognate 71 kDa protein | HSPA8 | 0.49 | 1.10 | 2.23 | 0.000 | 0.000 | 1 |
| P04792 | Heat shock protein beta-1 | HSPB1 | 1.03 | 3.59 | 3.47 | 0.014 | 0.053 | 1 |
| P61604 | 10 kDa heat shock protein, mitochondrial | HSPE1 | 0.84 | 2.73 | 3.25 | 0.000 | 0.000 | 1 |
| P01859 | Immunoglobulin heavy constant gamma 2 | IGHG2 | 0.49 | 0.65 | 1.31 | 0.011 | 0.044 | 1 |
| A0A0C4DH38 | Immunoglobulin heavy variable 5–51 | IGHV5–51 | 0.30 | 0.58 | 1.93 | 0.000 | 0.000 | 1 |
| A0A075B6K4 | Immunoglobulin lambda variable 3–10 | IGLV3–10 | 0.34 | 1.23 | 3.63 | 0.000 | 0.000 | 1 |
| A0A0B4J1Y8 | Immunoglobulin lambda variable 9–49 | IGLV9–49 | 0.47 | 0.87 | 1.86 | 0.000 | 0.000 | 1 |
| P07476 | Involucrin | IVL | 0.52 | 0.67 | 1.27 | 0.000 | 0.000 | 1 |
| P04264 | Keratin, type II cytoskeletal 1 | KRT1 | 0.58 | 0.83 | 1.43 | 0.016 | 0.058 | 1 |
| Q04695 | Keratin, type I cytoskeletal 17 | KRT17 | 0.24 | 1.38 | 5.83 | 0.000 | 0.000 | 1 |
| P35908 | Keratin, type II cytoskeletal 2 epidermal | KRT2 | 0.67 | 0.96 | 1.44 | 0.028 | 0.095 | 1 |
| P35527 | Keratin, type I cytoskeletal 9 | KRT9 | 0.49 | 0.79 | 1.62 | 0.005 | 0.024 | 1 |
| P13796 | Plastin-2 | LCP1 | 0.48 | 1.16 | 2.41 | 0.000 | 0.002 | 1 |
| Q08380 | Galectin-3-binding protein | LGALS3BP | 0.60 | 0.80 | 1.33 | 0.001 | 0.003 | 1 |
| P22079 | Lactoperoxidase | LPO | 0.84 | 1.61 | 1.92 | 0.000 | 0.001 | 1 |
| P02788 | Lactotransferrin | LTF | 0.63 | 2.09 | 3.31 | 0.000 | 0.003 | 1 |
| P40925 | Malate dehydrogenase, cytoplasmic | MDH1 | 0.88 | 1.57 | 1.79 | 0.002 | 0.010 | 1 |
| P14780 | Matrix metalloproteinase-9 | MMP9 | 0.98 | 1.67 | 1.72 | 0.004 | 0.019 | 1 |
| P80303 | Nucleobindin-2 | NUCB2 | 0.37 | 0.85 | 2.29 | 0.001 | 0.008 | 1 |
| P07237 | Protein disulfide-isomerase | P4HB | 0.69 | 1.14 | 1.64 | 0.010 | 0.039 | 1 |
| Q6MZM9 | Proline-rich protein 27 | PRR27 | 0.70 | 1.33 | 1.91 | 0.019 | 0.067 | 1 |
| P24158 | Myeloblastin | PRTN3 | 1.06 | 1.64 | 1.54 | 0.002 | 0.009 | 1 |
| P07602 | Prosaposin | PSAP | 0.32 | 1.35 | 4.22 | 0.000 | 0.000 | 1 |
| P05109 | Protein S100-A8 | S100A8 | 0.91 | 3.14 | 3.46 | 0.000 | 0.001 | 1 |
| P06702 | Protein S100-A9 | S100A9 | 0.91 | 2.97 | 3.26 | 0.000 | 0.000 | 1 |
| P48595 | Serpin B10 | SERPINB10 | 0.54 | 1.17 | 2.14 | 0.000 | 0.000 | 1 |
| P03973 | Antileukoproteinase | SLPI | 1.48 | 7.10 | 4.80 | 0.000 | 0.001 | 1 |
| P57768 | Sorting nexin-16 | SNX16 | 0.36 | 0.87 | 2.45 | 0.000 | 0.000 | 1 |
| Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | BAP1 | 3.89 | 2.67 | 0.69 | 0.000 | 0.000 | 2 |
| P47755 | F-actin-capping protein subunit alpha-2 | CAPZA2 | 1.76 | 1.52 | 0.86 | 0.000 | 0.000 | 2 |
| P16870 | Carboxypeptidase E | CPE | 0.76 | 0.52 | 0.68 | 0.004 | 0.018 | 2 |
| P07711 | Cathepsin L1 | CTSL | 0.79 | 0.77 | 0.97 | 0.004 | 0.017 | 2 |
| Q16610 | Extracellular matrix protein 1 | ECM1 | 1.23 | 1.37 | 1.11 | 0.000 | 0.000 | 2 |
| P24530 | Endothelin receptor type B | EDNRB | 1.37 | 0.49 | 0.35 | 0.003 | 0.015 | 2 |
| P01877 | Immunoglobulin heavy constant alpha 2 | IGHA2 | 1.48 | 0.99 | 0.67 | 0.000 | 0.000 | 2 |
| P01601 | Immunoglobulin kappa variable 1D-16 | IGKV1D-16 | 1.34 | 1.10 | 0.82 | 0.000 | 0.000 | 2 |
| P01042 | Kininogen-1 | KNG1 | 1.06 | 0.99 | 0.94 | 0.000 | 0.000 | 2 |
| P09382 | Galectin-1 | LGALS1 | 1.66 | 0.69 | 0.42 | 0.000 | 0.000 | 2 |
| O95274 | Ly6/PLAUR domain-containing protein 3 | LYPD3 | 1.13 | 0.87 | 0.77 | 0.006 | 0.024 | 2 |
| Q9NQR4 | Omega-amidase NIT2 | NIT2 | 1.09 | 0.89 | 0.82 | 0.000 | 0.000 | 2 |
| Q99497 | Protein/nucleic acid deglycase DJ-1 | PARK7 | 0.95 | 1.00 | 1.05 | 0.000 | 0.000 | 2 |
| Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | PYCARD | 1.14 | 1.10 | 0.97 | 0.000 | 0.000 | 2 |
| O00161 | Synaptosomal-associated protein 23 | SNAP23 | 2.35 | 0.95 | 0.40 | 0.017 | 0.060 | 2 |
| P04004 | Vitronectin | VTN | 1.44 | 1.31 | 0.91 | 0.015 | 0.056 | 2 |
| P62258 | 14–3–3 protein epsilon | YWHAE | 3.23 | 1.75 | 0.54 | 0.000 | 0.000 | 2 |
| Q9Y2Y4 | Zinc finger and BTB domain-containing protein 32 | ZBTB32 | 1.81 | 1.01 | 0.56 | 0.007 | 0.028 | 2 |