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. 2020 May 15;11:2420. doi: 10.1038/s41467-020-16214-8

Fig. 7. Landscape of accessible chromatin differentiates stem cell populations.

Fig. 7

a Volcano plot showing significant differences in DNA accessibility as measured using ATAC-seq between GCTM-2highCD9highEPCAMhigh (yellow) and GCTM-2midCD9mid (blue) populations (FDR < 0.01). Vertical lines indicate twofold difference. b Distribution of significantly different open chromatin regions plotted as distance from TSS. c Bar chart of the top 150-log odds ratios for overlap of differentially open chromatin regions in the GCTM-2midCD9mid (left) and GCTM-2highCD9highEPCAMhigh (right) populations compared with all ChIP-seq data for all cell types in the ENCODE TF dataset. Orange indicates ChIP data from the human ESC cell line H1. d Similar to c showing to 15 highest log odds ratios for overlap. Names of each TF antibody used for ChIP are indicated on the left.