Overexpression of PAICS in PDAC. Oncomine gene expression profiling showing PAICS expression from PDAC tissues as reported by (A) Segara et al., 2005 [36] and (B) Pei et al., 2009 [37]. (C) PAICS expression, determined by use of UALCAN [39], for PDACs compared to normal pancreatic tissue. (D) Stage-wise PAICS expression in pancreatic tumors. (E) Kaplan-Meier analysis of survival time for PDACs determined by use of UALCAN. (F) Representative images showing PAICS expression, assessed by immunohistochemistry, in PDACs. Hematoxylin was used for nuclear staining.