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. 2020 May 15;13(7):100776. doi: 10.1016/j.tranon.2020.100776

Figure 2.

Figure 2

PAICS knockdown reduced PDAC cell proliferation and colony formation. (A) Immunoblot analyses of PAICS protein levels in PANC-1 and S2VP10 cells treated with PAICS shRNA compared to levels in cells treated with NT shRNA. β-Actin was used as a loading control. (B) PAICS knockdown reduced cell proliferation at 2, 4, and 6 days. (C) Colony formation was suppressed at 10 days after seeding of 1000 shRNA-treated cells in six-well plates. Statistically significant differences (*P < .05) are indicated by an asterisk (*).