Fig. 4.
Effect of suppression of guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) on protein kinase B (Akt)/nuclear transcription factor-κB (NF-κB)/inhibitor of NF-κB (IκB) pathway after tumour necrosis factor α (TNF-α) treatment. Cells were incubated with 10 ng/ml TNF-α for zero, 15, 30, 60, or 120 minutes. Suppression of GNAQ induced several signalling pathways including protein kinase B (Akt) and inhibitor of NF-κB (IκB)/ nuclear transcription factor-κB (NF-κB).
