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. 2020 May 16;9(3):99–107. doi: 10.1302/2046-3758.93.BJR-2019-0089.R1

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© 2020 Author(s) et al

Open Access This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 2 — Cigarette smoke inhalation compromised fracture healing. a) Bone healing analysis with microCT and histological examination eight weeks after fracture revealed the union rate (n = 10). b) MicroCT imaging demonstrated the ratio of bone:tissue volume.( p = 0.006, Mann-Whitney U test) c) The ultimate load of biomechanical three-point bending test showed strength of healing bone. The contralateral femur served as an internal control (100%) (n = 6). (p = 0.013, Mann-Whitney U test) d) One representative sample is shown in each group with radiograph, microCT images, and histological sections with haematoxylin and eosin (H&E) staining. *Statistically significant.