Table 5.

Multivariate adjusted relations of TMTB-A and white matter microstructural integrity as assessed by Fractional anisotropy (FA) and radial diffusivity (RD) in participants with a cfPWV value above and below 8.5 m/s.

Participants with a cfPWV value above 8.5 m/s
DTI Metrics	ROI	B	β	p-value
FA	corpus callosum	−704.110	−0.510	0.008
	internal capsule	−505.337	−0.309	0.122
	corona radiata	−653.102	−0.404	0.040
	superior longitudinal fasciculus	−216.783	−0.180	0.363
RD	corpus callosum	6.28 105	0.560	0.003
	internal capsule	5.45 105	0.260	0.180
	corona radiata	8.12 105	0.520	0.004
	superior longitudinal fasciculus	3.89 105	0.322	0.092

Participants with a cfPWV value below 8.5 m/s
DTI Metrics	ROI	B	β	p-value
FA	corpus callosum	−28.923	−0.037	0.888
	internal capsule	−0.976	0.001	0.996
	corona radiata	70.943	0.082	0.742
	superior longitudinal fasciculus	73.245	0.119	0.648
RD	corpus callosum	9.40 105	0.172	0.551
	internal capsule	2.21 105	0.232	0.356
	corona radiata	9.90 105	0.158	0.565
	superior longitudinal fasciculus	3.79 105	0.060	0.823

Significant p-values (corrected for multiple comparisons) are in bold fonts (adjusted threshold is 0.006 and 0.018 for FA and RD respectively).