Table 6.
Multivariate adjusted relations of TMTB-A and white matter microstructural integrity as assessed by Fractional anisotropy (FA) and radial diffusivity (RD) in participants with a cfPWV value above and below 10 m/s.
| Participants with a cfPWV value above 10 m/s | ||||
|---|---|---|---|---|
| DTI Metrics | ROI | B | β | p-value |
| FA | corpus callosum | −388.324 | −0.501 | 0.106 |
| internal capsule | −315.331 | −0.358 | 0.256 | |
| corona radiata | −220.656 | −0.290 | 0.390 | |
| superior longitudinal fasciculus | −198.375 | −0.340 | 0.292 | |
| RD | corpus callosum | 2.37 105 | 0.363 | 0.277 |
| internal capsule | 3.94 105 | 0.405 | 0.203 | |
| corona radiata | 4.74 105 | 0.549 | 0.084 | |
| superior longitudinal fasciculus | 3.30 105 | 0.580 | 0.067 | |
| Participants with a cfPWV value below 10 m/s | ||||
|---|---|---|---|---|
| DTI Metrics | ROI | B | β | p-value |
| FA | corpus callosum | −380.274 | −0.317 | 0.073 |
| internal capsule | −201.212 | −0.159 | 0.365 | |
| corona radiata | −291.883 | −0.218 | 0.229 | |
| superior longitudinal fasciculus | −66.524 | −0.067 | 0.704 | |
| RD | corpus callosum | 4.55 105 | 0.483 | 0.007 |
| internal capsule | 3.16 105 | 0.193 | 0.267 | |
| corona radiata | 3.44 105 | 0.320 | 0.060 | |
| superior longitudinal fasciculus | 2.03 105 | 0.202 | 0.241 | |
Significant p-values (corrected for multiple comparisons) as indicated (adjusted treshold is 0.006 for FA and RD).