Table 1.

Effects of azilsartan, perindopril and combined groups on Y-maze test in AlCl₃ -induced Alzheimer’s disease in rats.

Groups	Spontaneous Alternation Percentage %
Negative Control	72 ± 0.85*
Vehicle	72.16 ± 0.87*
AlCl3 (100 mg/kg) - Positive control	45 ± 0.68
Azilsartan 1 (3.5 mg/kg)	71.33 ± 0.49*
Azilsartan 2 (7 mg/kg)	72.66 ± 0.84*
Perindopril 1 (0.5 mg/kg)	73.16 ± 0.70*
Perindopril 2 (1 mg/kg)	72.16 ± 0.94*
Combined 1 (Azilsartan 1 + Perindopril 1)	69.83 ± 0.60*
Combined 2 (Azilsartan 2 + Perindopril 2)	70.66 ± 1.20**

Values are expressed as means ± SEM, n = 6 rats.

^*P < 0.001 compared with the corresponding AlCl₃ group values; by one way ANOVA and Tukey HSD post hoc test.